Vuba aha, ibihangange bibiri by’itabi, PMI na BAT, byasohoye inyandiko z’ubushakashatsi mu binyamakuru mpuzamahanga by’ubuvuzi.Ibyavuye mu bushakashatsi byerekana ko ibicuruzwa bishya by’itabi nka e-itabi n’ubushyuhe-bidatwikwa bitangiza kandi bifite uburozi kuruta itabi gakondo, kandi bishobora kugabanya cyane ingaruka ku myanya y’ubuhumekero.kugirira nabi.
Mu gihe abantu bamenya ububi bw'itabi ryiyongera, e-itabi rirushaho kumenyekana na rubanda nk'igisimbuza itabi.Ariko, ingaruka ndende zo kuryoherwae-itabiuburyohe buvanze hamwe numwotsi w itabi kubanywa itabi biracyakomeza gushakishwa.
Vuba aha, PMI Philip Morris International yasohoye raporo y’ubushakashatsi “Isuzuma ry’ubumara bwo guhumeka umwotsi w’itabi na aerosole biva mu mvange ya flavour: ubushakashatsi bw’ibyumweru 5 mu mbeba za A / J” mu kinyamakuru cyo mu Bwongereza cy’uburozi “Ikinyamakuru cy’ubumenyi bw’uburozi”, gisobanura ibisobanuro birambuye yingingo zifitanye isano Intambwe yubushakashatsi nibisubizo.
Muri ubwo bushakashatsi, imbeba 87 z’abagabo n’imbeba 174 zidafite ishingiro n’inda zitwite zahawe inshingano ku matsinda 9 y’ubushakashatsi, kandi zikorerwa mu kirere, umwotsi w’itabi, hamwe na e-itabi ya aerosole hamwe n’ibice bitatu bitandukanye bya flavours, hejuru, hagati, na hasi.Kumenyekanisha kugeza kumasaha 6 kumunsi, iminsi 5 mucyumweru, ibyumweru 5 byakurikiwe na necropsy, uburemere bwumubiri hamwe nisuzuma rya histopathologique.
Ishusho yerekana amakuru yo gusuzuma ibihaha byimbeba.Birashobora kugaragara ko amakuru ajyanye nimbeba zerekanwa numwotsi w itabi afite igisubizo kigaragara (igice cyumutuku)
Ibisubizo by'ibizamini bya nyuma byerekanye ko igihe imbeba zagaragaraga kuri e-itabi ya aerosole ifite kandi idafite uburyohe, ugereranije n’abahuye n’umwotsi w’itabi, nta mpinduka nini zigeze zihinduka mu myanya y'ubuhumekero, izuru, na epiteliyale epithelale yerekanaga ko e-itabi. Sol ntikurakaza cyane ingirangingo ningingo bihuye.Ibisubizo byubushakashatsi byerekana kandi ko, ugereranije n’itabi gakondo,itabiirashobora kugabanya cyane ibihaha, kimwe no kwangirika kwizuru, umuhogo na epitelium ya tracheal.
BAT yo mu Bwongereza y'Abanyamerika Itabi yasohoye inyandiko y’ubushakashatsi yise “Isesengura Ry’ubushakashatsi no mu buryo bwa Vitro bwo guhuza ikiraro hagati y’ibicuruzwa bitandukanye bishyushye by’itabi” mu kinyamakuru cyitwa “Umusanzu w’itabi n’ubushakashatsi bwa Nikotine”, maze gikora ubushakashatsi kuri THP (ibicuruzwa bya HNB) Uburozi ikizamini.
Mu bushakashatsi bwakozwe, aerosole hamwe numwotsi w itabi byubwoko butanu bwa THP hamwe na THP imwe yibanze yakoreshejwe nkibidukikije, kandi cytotoxicity yasuzumwe nubuzima bwa selile epithelial selile.Ibisubizo byagaragaje ko reaction zose za cytotoxique mu itsinda rya THP zari munsi ya 95% ugereranije n’izo mu itsinda ry’itabi ry’itabi, kandi nta tandukaniro rikomeye ry’uburozi hagati ya THP eshanu zitandukanye na THP shingiro.
Nk’uko ubushakashatsi bubyerekana, iterambere n’itangwa ry’ibindi bicuruzwa by’itabi na nikotine biriyongera cyane, abaguzi bagenda bemera ibicuruzwa bishya nka THP, kandi umutekano wacyo ndetse n’ingaruka zabyo mu rwego rwo gusuzuma uburozi bikwiye kwitabwaho n’inganda.Gusa iyo ibicuruzwa byujuje ubuziranenge (harimo imikorere ya bateri) birashobora kurushaho kugira uruhare rwiza nkingamba zubuzima rusange.
Reba
Ee Tsin Wong, Karsta Luettich, Lydia Cammack, n'abandi.Isuzuma ry'ubumara bwo guhumeka umwotsi w itabi na aerosole biva muvanga uburyohe: ubushakashatsi bwibyumweru 5 mu mbeba za A / J.Ikinyamakuru cy’uburozi bwakoreshejwe, 2022
Tomasz Jaunky, David Thorne, Andrew Baxter, n'abandi.Isesengura Ryubushakashatsi no muri Vitro Uburyo bwo Kurambura Hagati Yibicuruzwa Bitandukanye Bishyushye Ibicuruzwa Bitandukanye.Umusanzu mu Itabi & Ubushakashatsi bwa Nikotine, 2022
Igihe cyo kohereza: Ukuboza-16-2022
